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Thymosin α-1 reconstitution calculator.

In human trialsCommon vials: 5, 10 mg

Thymosin alpha-1 is used clinically in several countries as Zadaxin, supplied as a 1.6 mg vial reconstituted with 1 mL of sterile water. Research vials are 5 mg or 10 mg, so the clinical figure and the vial in your hand rarely match.

Compound (optional, 69 in library)

Reference range often cited for Thymosin α-1: 1500–1600 mcg, shown for orientation only, not a recommendation. Enter your own target below. Read the evidence →

Draw to
10
units
Volume to draw
0.1
mL
At this amount
20
draws / vial
After one draw
4.75
mg left
Syringe · draw to 10 of 100 units
0
10
20
30
40
50
60
70
80
90
100

Each unit on a 100u · 1.0 mL syringe ≈ 25 mcg of this solution.

Concentration
2.5
mg / mL
Concentration
2,500
mcg / mL
Per U-100 unit
25
mcg / unit
Show the math
5 mg × 1000 = 5,000 mcg in the vial
2 mL × 100 = 200 U-100 units of liquid
5,000 mcg ÷ 200 units = 25 mcg per unit
250 mcg ÷ 25 mcg/unit = 10 units
10 units ÷ 100 = 0.1 mL
5,000 mcg ÷ 250 mcg = 20 draws per vial
Compare reconstitution volumes (5mg vial)
Water
mcg / unit
units for 250mcg
1 mL505
2 mL2510
2.5 mL2012.5
3 mL16.6715
5 mL1025

More water → lower concentration → more units for the same amount.

What changes the math for Thymosin α-1.

  • The clinical presentation gives 1,600 mcg/mL, and the labeled amount is the whole vial, which is why that format exists.
  • A 5 mg research vial in 2 mL is 2,500 mcg/mL instead. The same 1.6 mg target is then 64 units rather than the full 100.
  • Because the labeled figure is a whole vial, copying it onto a larger research vial overstates the amount considerably. Enter your own vial mass.

Formats and worked examples.

How Thymosin α-1 is actually administered, with the concentration arithmetic written out. Amounts in these tables are illustrative examples of the math, never a recommendation.

Thymosin α-1: research formats

Choose the format you are researching to see route-specific notes.

Used clinically (Zadaxin); 1.6 mg/vial SC injection is the standard format.

Thymosin α-1 (Zadaxin) is used clinically in several countries for immune modulation and chronic hepatitis B/C treatment. It is provided as a 1.6 mg lyophilized vial reconstituted with 1 mL sterile water (since clinical use is single-dose, sterile water rather than BAC water is supplied). Research contexts often mirror this format.

Clinical format: 1.6 mg vial + 1.0 mL sterile water (1,600 mcg/mL)
PHASEDAILY DOSEUNITS ON U-100VOLUME
Standard clinical dose1.6 mg (1,600 mcg)100 units1.00 mL
Titration schedule is reproduced from the FDA-approved prescribing information: a public regulatory fact, not a dosing recommendation from this site. Follow your prescriber's instructions.

FAQ.

How is Zadaxin reconstituted?

As a 1.6 mg lyophilized vial with 1 mL of sterile water, giving 1,600 mcg/mL, where the labeled amount is the vial's full contents. Where the approved product and its labeling apply, they govern.

How many units is 1.6 mg from a 5 mg vial?

On 5 mg in 2 mL (2,500 mcg/mL), 1.6 mg is 1,600 mcg, which is 64 units. The clinical 1 mL figure does not transfer, because the vial mass and volume are both different.

Is thymosin alpha-1 FDA-approved?

It is approved in a number of countries but not by the FDA, which is a distinction the site keeps strictly. The legal status page sets out where it stands.

Before you use any of this

This page is arithmetic on numbers you enter. It does not recommend an amount of Thymosin α-1, and nothing here is medical advice. For what the published evidence actually supports, read the Thymosin α-1 profile, and for regulatory status see is Thymosin α-1 legal. Reviewed June 1, 2026.

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Educational and research reference only. Not medical advice, diagnosis, or dosing guidance. Flag an error on this page
Compounds