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Sermorelin reconstitution calculator.

Research / preclinicalCommon vials: 5, 10 mg

Sermorelin was an approved drug once, sold as Geref before it was discontinued, and today it comes as a 5 mg or 10 mg compounded or research vial. Old labeled figures and current vial sizes do not line up, which is where the confusion starts.

Compound (optional, 69 in library)

Reference range often cited for Sermorelin: 200–500 mcg, shown for orientation only, not a recommendation. Enter your own target below. Read the evidence →

Draw to
10
units
Volume to draw
0.1
mL
At this amount
20
draws / vial
After one draw
4.75
mg left
Syringe · draw to 10 of 100 units
0
10
20
30
40
50
60
70
80
90
100

Each unit on a 100u · 1.0 mL syringe ≈ 25 mcg of this solution.

Concentration
2.5
mg / mL
Concentration
2,500
mcg / mL
Per U-100 unit
25
mcg / unit
Show the math
5 mg × 1000 = 5,000 mcg in the vial
2 mL × 100 = 200 U-100 units of liquid
5,000 mcg ÷ 200 units = 25 mcg per unit
250 mcg ÷ 25 mcg/unit = 10 units
10 units ÷ 100 = 0.1 mL
5,000 mcg ÷ 250 mcg = 20 draws per vial
Compare reconstitution volumes (5mg vial)
Water
mcg / unit
units for 250mcg
1 mL505
2 mL2510
2.5 mL2012.5
3 mL16.6715
5 mL1025

More water → lower concentration → more units for the same amount.

What changes the math for Sermorelin.

  • 5 mg in 2 mL is 2,500 mcg/mL, so 200 mcg is 8 units and 500 mcg is 20 units.
  • Compounded sermorelin is often dispensed already reconstituted with instructions from the pharmacy. If yours arrived as liquid, the concentration is on the label and there is nothing to compute.
  • Sermorelin has a short half-life, so it is administered frequently, which makes doses per vial the practical planning figure.

Formats and worked examples.

How Sermorelin is actually administered, with the concentration arithmetic written out. Amounts in these tables are illustrative examples of the math, never a recommendation.

Sermorelin: research formats

Choose the format you are researching to see route-specific notes.

Short-acting GHRH analog; administered before sleep to mimic the natural nocturnal GH pulse.

Sermorelin is typically sold as a 3 mg or 6 mg lyophilized vial. Reconstituting 3 mg with 3.0 mL BAC water gives 1,000 mcg/mL. Research protocols commonly target pre-sleep administration to coincide with the body's natural nocturnal GH peak.

Example math: 3 mg vial + 3.0 mL BAC water (1,000 mcg/mL)
PHASEDAILY DOSEUNITS ON U-100VOLUME
Low end200 mcg20 units0.20 mL
Mid300 mcg30 units0.30 mL
High end500 mcg50 units0.50 mL
This is not a dosing recommendation. Amounts shown are illustrative examples of the concentration math.

FAQ.

Is sermorelin FDA-approved?

It was, as Geref, and that product was discontinued. What is dispensed now comes through compounding or research supply, which is a different regulatory position. The legal status page covers the detail.

My pharmacy sent sermorelin already mixed. What do I enter?

Nothing needs reconstituting. The label states a concentration in mg/mL, and dividing your target by it gives the volume. The mcg to units converter handles that single step.

How many units is 300 mcg of sermorelin?

On 5 mg in 2 mL (2,500 mcg/mL) it is 12 units. On 5 mg in 5 mL it is 30 units. Enter your own vial and water above rather than copying either figure.

Before you use any of this

This page is arithmetic on numbers you enter. It does not recommend an amount of Sermorelin, and nothing here is medical advice. For what the published evidence actually supports, read the Sermorelin profile, and for regulatory status see is Sermorelin legal. Reviewed June 1, 2026.

Reconstitution calculators for other compounds
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Different question? The general reconstitution calculator covers every compound on the site, the blend calculator handles multi-peptide stacks, and vial longevity turns a vial into weeks of supply.

Stop re-deriving this every vial

PepCue remembers your Sermorelin vial, concentration, and draw, then tracks every dose against it. Free.

Educational and research reference only. Not medical advice, diagnosis, or dosing guidance. Flag an error on this page
Compounds