PT-141 reconstitution calculator.
PT-141 is bremelanotide, approved as Vyleesi in a fixed single-use autoinjector that needs no mixing. Research vials are typically 10 mg, which is a large mass against targets discussed in the low milligrams.
Reference range often cited for PT-141: 1000–2000 mcg, shown for orientation only, not a recommendation. Enter your own target below. Read the evidence →
Each unit on a 100u · 1.0 mL syringe ≈ 50 mcg of this solution.
Show the math
More water → lower concentration → more units for the same amount.
What changes the math for PT-141.
- 10 mg in 2 mL is 5,000 mcg/mL, so 1 mg is 20 units and 2 mg is 40 units.
- The approved autoinjector delivers a fixed amount by design. A vial gives you an arbitrary concentration instead, which is precisely why the arithmetic matters.
- A 10 mg vial holds many draws at milligram scale, so the reconstituted stability window is usually the limit rather than the peptide running out.
Formats and worked examples.
How PT-141 is actually administered, with the concentration arithmetic written out. Amounts in these tables are illustrative examples of the math, never a recommendation.
PT-141: research formats
Choose the format you are researching to see route-specific notes.
Vyleesi is an FDA-approved auto-injector; research use from 10 mg vials also exists.
PT-141 (bremelanotide) is FDA-approved as Vyleesi (1.75 mg/0.3 mL auto-injector) for hypoactive sexual desire disorder in premenopausal women. Research contexts also use lyophilized 10 mg vials reconstituted with BAC water.
Research-use vials: 10 mg + 2.0 mL BAC water = 5,000 mcg/mL. At this concentration, 250–500 mcg = 5–10 units on a U-100 syringe.
The FDA label for Vyleesi specifies SC administration in the abdomen or thigh, at least 45 minutes before anticipated sexual activity. No more than one dose per 24 hours.
FAQ.
Is Vyleesi the same as a PT-141 vial?
Same molecule, different presentation. Vyleesi is an FDA-approved single-use autoinjector with a fixed labeled amount. A lyophilized vial has no label governing it and a concentration you set yourself.
How many units is 1.75 mg of PT-141?
On 10 mg in 2 mL (5,000 mcg/mL), 1.75 mg is 1,750 mcg, which is 35 units. Change the water volume and that figure moves proportionally.
Why is my draw so small?
A 10 mg vial in a small volume is concentrated. If a target lands in the first few units, adding water spreads the same amount across more of the barrel and makes it readable.
This page is arithmetic on numbers you enter. It does not recommend an amount of PT-141, and nothing here is medical advice. For what the published evidence actually supports, read the PT-141 profile, and for regulatory status see is PT-141 legal. Reviewed June 1, 2026.
Different question? The general reconstitution calculator covers every compound on the site, the blend calculator handles multi-peptide stacks, and vial longevity turns a vial into weeks of supply.
PepCue remembers your PT-141 vial, concentration, and draw, then tracks every dose against it. Free.