Cagrilintide reconstitution calculator.
A 5 mg vial of Cagrilintide dissolved in 2 mL of bacteriostatic water is 2,500 mcg per mL, which is 25 mcg per unit on a U-100 insulin syringe.
Cagrilintide is an investigational once-weekly amylin analog and is not FDA-approved, so there is no label, no manufacturer reconstitution instruction, and no reference concentration to copy. It is also not a GLP-1 agonist, which matters because it comes in 5 mg and 10 mg vials, two of the same sizes as semaglutide, and the two get read off the same tables. A semaglutide table only gives the right units for cagrilintide when the vial mass and water volume happen to match exactly.
Each unit on a 100u · 1.0 mL syringe ≈ 25 mcg of this solution.
Show the math
More water → lower concentration → more units for the same amount.
How much bacteriostatic water for a Cagrilintide vial?
There is no single correct volume. More water gives a weaker solution, so each unit on the syringe holds less Cagrilintide and a given amount takes more units to measure, which is easier to read on the syringe scale. Less water does the opposite. These tables show the concentration for each common vial size across the usual volumes. They are arithmetic, not a recommendation of how much to take.
| BAC water | Concentration | Per 1 unit | Per 10 units |
|---|---|---|---|
| 1 mL | 5,000 mcg/mL | 50 mcg | 500 mcg |
| 1.5 mL | 3,333 mcg/mL | 33.3 mcg | 333 mcg |
| 2 mL | 2,500 mcg/mL | 25 mcg | 250 mcg |
| 2.5 mL | 2,000 mcg/mL | 20 mcg | 200 mcg |
| 3 mL | 1,667 mcg/mL | 16.7 mcg | 167 mcg |
| BAC water | Concentration | Per 1 unit | Per 10 units |
|---|---|---|---|
| 1 mL | 10,000 mcg/mL | 100 mcg | 1,000 mcg |
| 1.5 mL | 6,667 mcg/mL | 66.7 mcg | 667 mcg |
| 2 mL | 5,000 mcg/mL | 50 mcg | 500 mcg |
| 2.5 mL | 4,000 mcg/mL | 40 mcg | 400 mcg |
| 3 mL | 3,333 mcg/mL | 33.3 mcg | 333 mcg |
How many units of Cagrilintide is a given amount?
Divide the amount in micrograms by the micrograms per unit for your mix. With a solution of 2,500 mcg per mL, one unit on a U-100 syringe holds 25 mcg, so any amount in mcg divided by 25 gives the units. The calculator above does this for you from your own vial and water, and the tables give the per-unit figure for each common mix.
Why does Cagrilintide need its own calculation?
- 5 mg in 2 mL is 2,500 mcg/mL, so 1 mg is 40 units. A 10 mg vial in the same 2 mL is 5,000 mcg/mL, where the same 1 mg is 20 units. Trial amounts are written in mg, so enter mg and let the tool convert rather than adding zeros by hand.
- CagriSema, the combination filed with the FDA in December 2025, is cagrilintide and semaglutide co-formulated by the manufacturer at a fixed ratio in a single injection. Two research vials are not that product: each has its own concentration, and a unit count from one never applies to the other. The blend calculator works out both side by side.
- Cagrilintide carries a fatty-acid chain that slows its clearance, which is why it was developed for once-weekly injection. With one draw a week, the reconstituted stability window can end a vial before the peptide runs out, and the vial longevity calculator turns a vial into weeks.
- Published amounts come from the REDEFINE and REIMAGINE trial programs rather than a label. Those are trial facts, not instructions, and the compound profile covers what the trials actually measured.
How is Cagrilintide administered, and what does the math look like?
How Cagrilintide is actually administered, with the concentration arithmetic written out. Amounts in these tables are illustrative examples of the math, never a recommendation.
Cagrilintide: research formats
Choose the format you are researching to see route-specific notes.
Long-acting lipidated amylin analog given once weekly in trials. Not approved as a standalone drug.
Cagrilintide is a once-weekly lipidated amylin analog studied both as a monotherapy and as the amylin half of the fixed-dose combination CagriSema. It is investigational, so there is no marketed standalone presentation and no labeled titration schedule.
The fatty-acid acylation is what makes weekly administration possible; it slows clearance of a hormone analog that would otherwise be far shorter-acting.
Novo Nordisk filed an NDA for the CagriSema combination in December 2025. Cagrilintide alone remains unapproved.
Cagrilintide reconstitution: common questions
Is cagrilintide FDA-approved?
No. Cagrilintide on its own is investigational and has no approved product. The combination CagriSema was submitted to the FDA in December 2025, and the legal status page tracks where it stands. A lyophilized research vial is not an approved product of any kind.
How many units is 1 mg of cagrilintide?
On a 5 mg vial in 2 mL (2,500 mcg/mL), 1 mg is 1,000 mcg, which is 40 units on a U-100 syringe. On a 10 mg vial in 2 mL (5,000 mcg/mL) it is 20 units. 1 mg is used here as a round number for the arithmetic, not as a reference amount.
Can I use a semaglutide reconstitution chart for cagrilintide?
Only if the vial mass and water volume match exactly. The arithmetic is the same mass divided by volume, but a chart describes one vial at one water volume, not a compound. Enter your own cagrilintide vial and water above and the units follow from those.
What the evidence on Cagrilintide actually shows
Knowing the concentration is not the same as knowing whether to use it. These are the strongest studies behind the Cagrilintide profile, labelled with the study type PubMed itself assigns.
- Randomized controlled trial · 2026Cagrilintide-semaglutide (CagriSema) versus semaglutide or cagrilintide in people with type 2 diabetes (REIMAGINE 2): a double-blind, randomised, controlled, phase 3 studyThe lancet. Diabetes & endocrinology · PMID 42251859
- Randomized controlled trial · 2025Coadministered Cagrilintide and Semaglutide in Adults with Overweight or ObesityThe New England journal of medicine · PMID 40544433
- Journal article · 2025Cagrilintide lowers bodyweight through brain amylin receptors 1 and 3EBioMedicine · PMID 40609154
This page is arithmetic on numbers you enter. It does not recommend an amount of Cagrilintide, and nothing here is medical advice. For what the published evidence actually supports, read the Cagrilintide profile, and for regulatory status see is Cagrilintide legal. Reviewed June 1, 2026.
Different question? The general reconstitution calculator covers every compound on the site, the blend calculator handles multi-peptide stacks, and vial longevity turns a vial into weeks of supply.
PepCue remembers your Cagrilintide vial, concentration, and draw, then tracks every dose against it. Free.