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HGH Fragment 176-191 reconstitution calculator.

Research / preclinicalCommon vials: 2, 5 mg

The 176-191 fragment is the lipolytic tail of growth hormone, sold as 2 mg and 5 mg vials. It is not HGH and is not dosed in international units, which is the single most common mistake made with it.

Compound (optional, 69 in library)

Reference range often cited for HGH Fragment 176-191: 250–500 mcg, shown for orientation only, not a recommendation. Enter your own target below. Read the evidence →

Draw to
25
units
Volume to draw
0.25
mL
At this amount
8
draws / vial
After one draw
1.75
mg left
Syringe · draw to 25 of 100 units
0
10
20
30
40
50
60
70
80
90
100

Each unit on a 100u · 1.0 mL syringe ≈ 10 mcg of this solution.

Concentration
1
mg / mL
Concentration
1,000
mcg / mL
Per U-100 unit
10
mcg / unit
Show the math
2 mg × 1000 = 2,000 mcg in the vial
2 mL × 100 = 200 U-100 units of liquid
2,000 mcg ÷ 200 units = 10 mcg per unit
250 mcg ÷ 10 mcg/unit = 25 units
25 units ÷ 100 = 0.25 mL
2,000 mcg ÷ 250 mcg = 8 draws per vial
Compare reconstitution volumes (2mg vial)
Water
mcg / unit
units for 250mcg
1 mL2012.5
2 mL1025
2.5 mL831.25
3 mL6.6737.5
5 mL462.5

More water → lower concentration → more units for the same amount.

What changes the math for HGH Fragment 176-191.

  • 5 mg in 2 mL is 2,500 mcg/mL, so 250 mcg is 10 units and 500 mcg is 20 units.
  • HGH is measured in IU against a WHO standard. This fragment is measured by mass in mcg, so IU conversions do not apply to it at all.
  • The 2 mg vial is common and halves the concentration at the same water volume, so check which you have before reading any table.

Formats and worked examples.

How HGH Fragment 176-191 is actually administered, with the concentration arithmetic written out. Amounts in these tables are illustrative examples of the math, never a recommendation.

HGH Fragment 176-191: research formats

Choose the format you are researching to see route-specific notes.

Same reconstitution profile as AOD-9604: acetic acid first, then BAC water to volume.

HGH Fragment 176-191 is the C-terminal 16-residue fragment of human growth hormone and is closely related to AOD-9604, the modified analog carrying an extra N-terminal tyrosine. Like other aggregation-prone GH fragments it is typically reconstituted with 0.6% acetic acid first, then diluted with BAC water. A 5 mg vial brought to 2.0 mL gives 2,500 mcg/mL.

Example math: 5 mg vial + 2.0 mL (acetic acid + BAC water) (2,500 mcg/mL)
PHASEDAILY DOSEUNITS ON U-100VOLUME
Example low250 mcg10 units0.10 mL
Example mid500 mcg20 units0.20 mL
This is not a dosing recommendation. Amounts shown are illustrative examples of the concentration math.

Almost all of the supporting data belong to the analog AOD-9604, not to the plain 176-191 fragment. AOD-9604 reached human obesity trials and did not produce clinically meaningful weight loss beyond placebo, and the unmodified fragment has essentially no controlled human evidence of its own.

The two are not interchangeable: an added N-terminal tyrosine is a real structural difference, so data from one does not transfer cleanly to the other.

FAQ.

How many IU is HGH fragment 176-191?

The question does not apply. IU is a measure of biological activity defined against a standard for somatropin, and no such standard exists for this fragment. It is measured by mass, in mcg.

How many units is 300 mcg?

On 5 mg in 2 mL (2,500 mcg/mL) it is 12 units. On a 2 mg vial in the same 2 mL (1,000 mcg/mL) it is 30 units.

Is the fragment the same as HGH?

No. It is a fragment of the C-terminal region, and the compound profile covers what the human evidence does and does not show for it, which is not the same evidence base as somatropin.

Before you use any of this

This page is arithmetic on numbers you enter. It does not recommend an amount of HGH Fragment 176-191, and nothing here is medical advice. For what the published evidence actually supports, read the HGH Fragment 176-191 profile, and for regulatory status see is HGH Fragment 176-191 legal. Reviewed June 1, 2026.

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Educational and research reference only. Not medical advice, diagnosis, or dosing guidance. Flag an error on this page
Compounds