PepCue vs Shotsy.
This is the clearest case on the site of two apps that are not really competing. Shotsy is focused on GLP-1 weight-loss tracking: one compound, one goal, a shot log and a weight trend. PepCue is built for people running several compounds at once who also want to know what the evidence behind each of them actually says. If you are on semaglutide or tirzepatide and nothing else, the narrower tool is very likely the better tool, and it would be dishonest to pretend otherwise.
Last checked September 2026. Competitor features and pricing change, so verify on their own site or App Store listing before you decide.
You are running more than one compound, or you want the evidence behind what you are taking graded and sourced, or you need vial reconstitution and syringe-unit math rather than a pen click count.
You are on a single GLP-1 for weight loss and you want the simplest possible tracker for exactly that. Narrow focus is a feature, not a shortcoming, and an app that does one job is faster to use than an app that does nine.
What we can state about Shotsy is that it is focused on GLP-1 weight-loss tracking rather than multi-peptide protocols. We have not verified its current pricing, its feature list or its ratings, so none of those appear in the table below.
Side by side, verifiable rows only.
| PepCue | Shotsy | |
|---|---|---|
| Price | Free to use. You can run a full protocol without paying, and there is no subscription gate on logging, schedules, the calculators or the evidence library. | Not verified. Check the App Store listing for current pricing. |
| Account required | Not required. Tracking starts without an account, and the browser calculators need no sign-up either. | Not verified |
| Scope | Multi-compound protocols across 69 profiled compounds, including GLP-1s, growth-hormone secretagogues, repair peptides and cosmetics. | Focused on GLP-1 weight-loss tracking rather than multi-peptide protocols. |
| Evidence grading | Every compound carries an S to F evidence tier scored on six axes: human evidence, preclinical depth, mechanism confidence, safety clarity, regulatory clarity and practical relevance. | Not verified |
| Scoring model published | Yes. The full six-axis model, the tier thresholds and a worked example on a real compound are published on the methodology page. | Not verified |
| Citations | 306 cited sources across 69 compound profiles, plus a generated research index of 274 unique PubMed records, every one pulled from NCBI and re-resolved against live PubMed by an audit script kept in the repo. | Not verified |
| Reconstitution and syringe math | 9, free in the browser with no account and no install: reconstitution, blends, GLP-1 titration, pen clicks, vial longevity, unit conversions and BAC water. | Not verified |
| Cost tracking | Enter a vial price and PepCue reports per-dose, weekly, monthly and yearly spend plus days of supply left. | Not verified |
| Schedules and reminders | Per-compound schedules with reminders, a calendar that stamps itself as you log, and a month view of every dose taken. | Not verified |
| Affiliate codes or vendor rankings | None. PepCue sells no peptides, ranks no vendors, takes no kickbacks and places no affiliate codes. | Not verified |
| Dosing guidance | Never. PepCue explains compounds and does the arithmetic on numbers you enter. It does not tell anyone what to take. | Not verified |
| Where your data lives | Protocols, doses, inventory, weights and check-ins are stored on your device rather than on our servers. | Not verified |
What PepCue does differently.
The split here is scope, and scope is the whole argument. A GLP-1 weight-loss tracker can assume a great deal: one compound, a pen rather than a vial, a weekly cadence, and weight as the outcome that matters. Every one of those assumptions lets the interface get simpler, and simpler is genuinely better when the assumptions hold. PepCue cannot make any of them, because the person it is built for might be running a GLP-1 alongside a growth-hormone secretagogue and a repair peptide, reconstituting powder from vials at three different concentrations, on three different schedules.
That is why the calculator layer exists and why it is on the open web rather than behind an install. Reconstitution is where people get hurt: you have a vial in milligrams, you add bacteriostatic water in millilitres, and you need an answer in syringe units for a dose expressed in micrograms. Get a decimal place wrong and the error is an order of magnitude. 9 calculators cover that arithmetic free, with no account, including blends, vial longevity, pen clicks and unit conversion. They compute on what you enter and suggest nothing.
The second difference is the library. Every compound on PepCue carries an S to F evidence tier computed from six scored axes, with the model published rather than asserted, and across 69 profiles there are 306 cited sources, and a generated research index holds 274 unique PubMed records re-checked against NCBI by an audit script in the repo. For a GLP-1 that layer is arguably the least interesting, because the approved GLP-1 receptor agonists have the strongest human evidence base of anything on this site, with large randomised outcome trials behind them. The library earns its keep the moment someone adds a second compound that does not have that, which is most of them.
There are no affiliate codes, no vendor rankings and nothing for sale anywhere on PepCue, and the site never tells anyone what to take. That matters more in the multi-compound world than in the single-GLP-1 one, because the research-chemical market is where the incentives get ugly.
Where Shotsy is stronger.
Shotsy is better at the job it was built for, and that is not a polite concession. An app scoped to one compound and one outcome can put the next shot, the last weight and the trend on a single screen without a compound picker, a concentration field or a protocol concept in the way. If you are on a GLP-1 for weight loss and you are never going to run anything else, that focus will make your life easier than a general-purpose protocol tracker will.
Pen-based GLP-1 use also sidesteps the hardest part of what PepCue exists to handle. There is no reconstitution, no bacteriostatic water and no syringe-unit conversion when the medication arrives in a prefilled pen with a dial. A tool built around that reality can be simpler because the reality is simpler.
A narrower app is also easier to stay consistent with, and adherence is the thing that actually determines whether GLP-1 treatment works. If the simpler interface means you log every week instead of most weeks, that is worth more than any feature comparison on this page.
FAQ.
Should I use Shotsy or PepCue for semaglutide?
If semaglutide is the only thing you are tracking and weight is the outcome you care about, Shotsy is built for exactly that and the narrower tool is likely the better fit. PepCue makes more sense if you are running other compounds alongside it, if you are working from vials rather than a pen, or if you want the evidence behind each compound graded and sourced.
Does PepCue handle GLP-1s?
Yes. GLP-1 receptor agonists are profiled on the site with their trial evidence, and the calculators include GLP-1 titration and a pen-click converter alongside the vial reconstitution math. PepCue does not tell anyone what dose to take at any stage; the calculators do arithmetic on numbers you enter.
How much does Shotsy cost?
We have not verified Shotsy's current pricing, so we are not going to print a number. Check their App Store listing. PepCue is free to use, and a full protocol can be run without paying.
Can PepCue track weight the way a weight-loss app does?
PepCue charts weight trends and week-over-week change alongside logged doses and estimated levels. It is a protocol tracker that includes weight rather than a weight-loss app that includes injections, which is a real difference in emphasis if weight is the only number you care about.
Last checked September 2026. Competitor features and pricing change, so verify on their own site or App Store listing before you decide.