Randomized controlled trialHumanClinical Trial, Phase III

Orforglipron Added to Titrated Insulin Glargine in Type 2 Diabetes: The ACHIEVE-5 Randomized Clinical Trial

JAMA, 2026 Aug 4. Giorgino F, D'Souza S, Ludwig L and 7 others.

Study type

Randomized controlled trial · Clinical Trial, Phase III

Subjects

Human participants (PubMed MeSH: Humans)

Journal

JAMA

Published

2026 Aug 4

PubMed

PMID 42251769 ↗

DOI

10.1001/jama.2026.9512 ↗

Full text

Free on PubMed Central (PMC13244277) ↗

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Indexed under

MeSH terms assigned by the National Library of Medicine.

AdultAgedFemaleHumansMaleMiddle AgedBlood GlucoseDiabetes Mellitus, Type 2Double-Blind MethodDrug Therapy, CombinationGlucagon-Like Peptide-1 Receptor AgonistsGlycated Hemoglobin

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