Randomized controlled trialHumanClinical Trial, Phase I

Daily Oral GLP-1 Receptor Agonist Orforglipron for Adults with Obesity

The New England journal of medicine, 2023 Sep 7. Wharton S, Blevins T, Connery L and 11 others.

Study type
Randomized controlled trial · Clinical Trial, Phase I
Subjects
Human participants (PubMed MeSH: Humans)
Journal
The New England journal of medicine
Published
2023 Sep 7
PubMed
PMID 37351564 ↗
DOI
10.1056/NEJMoa2302392 ↗

Where PepCue cites this

This paper is part of the evidence base behind this profile. Citing a study is not an endorsement of the compound: papers that found no effect are indexed the same way.

Orforglipron →

Indexed under

MeSH terms assigned by the National Library of Medicine.

AdultHumansAdministration, OralAnti-Obesity AgentsDiabetes Mellitus, Type 2Double-Blind MethodGlucagon-Like PeptidesHypoglycemic AgentsObesityWeight LossGlucagon-Like Peptide-1 Receptor Agonists

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Randomized controlled trial · 2026
Orforglipron for maintenance of body weight reduction: the double-blind, randomized phase 3b ATTAIN-MAINTAIN trial
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Orforglipron Added to Titrated Insulin Glargine in Type 2 Diabetes: The ACHIEVE-5 Randomized Clinical Trial
Randomized controlled trial · 2025
Orforglipron, an Oral Small-Molecule GLP-1 Receptor Agonist, in Early Type 2 Diabetes
Randomized controlled trial · 2025
Orforglipron, an Oral Small-Molecule GLP-1 Receptor Agonist for Obesity Treatment
Randomized controlled trial · 2023
Efficacy and safety of oral orforglipron in patients with type 2 diabetes: a multicentre, randomised, dose-response, phase 2 study

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Compounds