Randomized controlled trialHumanClinical Trial, Phase III

Orforglipron for maintenance of body weight reduction: the double-blind, randomized phase 3b ATTAIN-MAINTAIN trial

Nature medicine, 2026 Jul. Aronne LJ, Horn DB, le Roux CW and 11 others.

Study type
Randomized controlled trial · Clinical Trial, Phase III
Subjects
Human participants (PubMed MeSH: Humans)
Journal
Nature medicine
Published
2026 Jul
PubMed
PMID 42120723 ↗
DOI
10.1038/s41591-026-04386-7 ↗
Full text
Free on PubMed Central (PMC13375559) ↗

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Indexed under

MeSH terms assigned by the National Library of Medicine.

HumansDouble-Blind MethodWeight LossSemaglutideObesityFemaleMaleMiddle AgedTirzepatideAdultGlucagon-Like PeptidesOxadiazoles

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Compounds