Randomized controlled trialHumanClinical Trial, Phase III

Efficacy and safety of co-administered cagrilintide and semaglutide versus semaglutide alone in adults with overweight or obesity with or without type 2 diabetes in Japan and Taiwan (REDEFINE 5): a multicentre, randomised, active-controlled, phase 3a trial

The lancet. Diabetes & endocrinology, 2026 Jun. Yamauchi T, Becker NP, Hagemann CA and 8 others.

Study type
Randomized controlled trial · Clinical Trial, Phase III
Subjects
Human participants (PubMed MeSH: Humans)
Journal
The lancet. Diabetes & endocrinology
Published
2026 Jun
PubMed
PMID 42009015 ↗
DOI
10.1016/S2213-8587(25)00402-4 ↗

Where PepCue cites this

This paper is part of the evidence base behind this profile. Citing a study is not an endorsement of the compound: papers that found no effect are indexed the same way.

CagriSema →

Indexed under

MeSH terms assigned by the National Library of Medicine.

AdultAgedFemaleHumansMaleMiddle AgedDiabetes Mellitus, Type 2Double-Blind MethodDrug Therapy, CombinationHypoglycemic AgentsJapanObesity

Other papers on CagriSema

Randomized controlled trial · 2025
Cagrilintide-Semaglutide in Adults with Overweight or Obesity and Type 2 Diabetes
Randomized controlled trial · 2025
Coadministered Cagrilintide and Semaglutide in Adults with Overweight or Obesity

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Compounds