IGF-1 pathway

Downstream growth signalling mediated by insulin-like growth factor 1.

Much of growth hormone's anabolic effect is mediated by IGF-1, produced largely by the liver in response to GH. IGF-1 and its analogs act on growth and tissue pathways; this axis is the downstream end of growth-hormone-axis signalling.

Peptides acting through this pathway

igf-1-lr3peg-mgfhuman-growth-hormone

FAQ

What does igf-1 pathway do?

Much of growth hormone's anabolic effect is mediated by IGF-1, produced largely by the liver in response to GH. IGF-1 and its analogs act on growth and tissue pathways; this axis is the downstream end of growth-hormone-axis signalling.

Which peptides act through igf-1 pathway?

IGF 1 LR3, PEG MGF, Human Growth Hormone. They share this pathway but differ in evidence, approval, and safety.

Does this mechanism prove a peptide works?

No. Mechanistic plausibility is not proof of clinical benefit — a plausible pathway is a reason to study a compound, not evidence that it works in humans.

Keep reading
Peptide classes

How compounds group structurally.

The peptide database

Compounds organised by what they do.

Peptides 101

The biology behind the pathways.

Glossary

Receptors, agonists, half-life — defined.

Mechanistic plausibility is not proof of clinical benefit. Research reference only — not medical advice.

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