Mod-GRF (1-29) alternatives.

10 compounds compared to Mod-GRF (1-29), ranked by published evidence tier and regulatory status, not by what's marketed hardest.

Why people look for an alternative

Mod GRF 1-29 is chosen by people who specifically did not want the long-acting DAC version, so alternatives searches here are rarely about duration. They are about standing. It uses the same tetra-substituted GHRH(1-29) backbone as CJC-1295 without the albumin-binding linker, is not approved by the FDA or any major regulator, and falls under WADA Prohibited List class S2. The interesting fact for anyone comparing: its unmodified parent, sermorelin, was actually FDA-approved before being commercially discontinued, and the four engineered substitutions here exist only to slow enzymatic breakdown of that same sequence. Tesamorelin remains the one GHRH analog with a live approval.

What you're comparing against
Mod-GRF (1-29)
F tier · 29/100Research / preclinical

Mod GRF 1-29 (commonly sold as "CJC-1295 without DAC") is a synthetic 29-amino-acid analog of growth hormone-releasing hormone (GHRH).

Ranked by evidence · strongest first
  1. 01
    Tesamorelin
    A tierFDA-approved
    Egrifta

    Acts through the ghrh signalling pathway, like Mod-GRF (1-29). FDA-approved.

  2. 02
    Sermorelin
    C tierResearch / preclinical

    Acts through the ghrh signalling pathway, like Mod-GRF (1-29). Research / preclinical.

  3. 03
    CJC-1295
    F tierResearch / preclinical

    Acts through the ghrh signalling pathway, like Mod-GRF (1-29). Research / preclinical.

  4. 04
    CJC-1295 DAC
    F tierResearch / preclinical

    Acts through the ghrh signalling pathway, like Mod-GRF (1-29). Research / preclinical.

  5. 05
    Human Growth Hormone
    S tierFDA-approved
    HGH · somatropin

    Same category: growth hormone. FDA-approved.

  6. 06
    ACE-031
    D tierIn human trials
    ramatercept · ActRIIB-Fc

    Same category: growth hormone. In human trials.

  7. 07
    GHRP-1
    D tierResearch / preclinical
    growth hormone-releasing peptide-1

    Same category: growth hormone. Research / preclinical.

  8. 08
    GHRP-2
    D tierResearch / preclinical

    Same category: growth hormone. Research / preclinical.

  9. 09
    GHRP-6
    D tierResearch / preclinical

    Same category: growth hormone. Research / preclinical.

  10. 10
    Hexarelin
    D tierResearch / preclinical

    Same category: growth hormone. Research / preclinical.

How this list is built

An “alternative” here means a compound that shares Mod-GRF (1-29)'s mechanism pathway or sits in the same category, not a marketing substitute. Each is ordered by PepCue's evidence tier (a weighted 0–100 score across human data, safety, replication and regulatory clarity), then by whether it's actually approved. This is a research reference, not medical or purchasing advice: an alternative sitting higher on evidence does not mean it's right, safe, or legal for any given use. Reviewed June 1, 2026.

Comparing options with your provider?

PepCue keeps every compound, dose and lab in one private, provider-ready timeline, whichever one you land on.

Educational and research reference only. Not medical advice, diagnosis, or dosing guidance. Flag an error on this page
Compounds