Mitochondrial peptide signalling

Mitochondria-derived peptides studied in metabolism and stress responses.

Mitochondria-derived peptides such as MOTS-c and humanin, and mitochondrially-targeted peptides such as SS-31, are studied for roles in mitochondrial function, metabolism, and cellular stress responses — predominantly in preclinical settings.

Peptides acting through this pathway

mots-chumaninss-31

FAQ

What does mitochondrial peptide signalling do?

Mitochondria-derived peptides such as MOTS-c and humanin, and mitochondrially-targeted peptides such as SS-31, are studied for roles in mitochondrial function, metabolism, and cellular stress responses — predominantly in preclinical settings.

Which peptides act through mitochondrial peptide signalling?

Mots C, Humanin, SS 31. They share this pathway but differ in evidence, approval, and safety.

Does this mechanism prove a peptide works?

No. Mechanistic plausibility is not proof of clinical benefit — a plausible pathway is a reason to study a compound, not evidence that it works in humans.

Keep reading
Peptide classes

How compounds group structurally.

The peptide database

Compounds organised by what they do.

Peptides 101

The biology behind the pathways.

Glossary

Receptors, agonists, half-life — defined.

Mechanistic plausibility is not proof of clinical benefit. Research reference only — not medical advice.

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