GHRH signalling
Stimulating the pituitary's GHRH receptor to release growth hormone.
Growth-hormone-releasing hormone (GHRH) analogs activate the pituitary GHRH receptor, prompting pulsatile growth-hormone release. They raise the body's own GH output rather than supplying GH directly.
Peptides acting through this pathway
FAQ
What does ghrh signalling do?
Growth-hormone-releasing hormone (GHRH) analogs activate the pituitary GHRH receptor, prompting pulsatile growth-hormone release. They raise the body's own GH output rather than supplying GH directly.
Which peptides act through ghrh signalling?
Sermorelin, CJC 1295, CJC 1295 DAC, MOD GRF 1 29, Tesamorelin. They share this pathway but differ in evidence, approval, and safety.
Does this mechanism prove a peptide works?
No. Mechanistic plausibility is not proof of clinical benefit — a plausible pathway is a reason to study a compound, not evidence that it works in humans.
Mechanistic plausibility is not proof of clinical benefit. Research reference only — not medical advice.